Evidence from the field demonstrates that a comprehensive approach to global health can save lives, reduce costs and increase impact. Strengthening health systems requires a holistic approach to health: from developing new tools that are designed to reach the underserved even in remote areas, to increasing access to proven tools and interventions with an emphasis on strengthening health systems, to promoting an integrated approach for healthcare interventions. Panelists will present a more comprehensive approach to global health through cases examples from their work that link the entire value chain for health from early stage product research and development, through health systems strengthening, to healthcare delivery, and ultimately to economic and human development.